A Study of Senile VaginitisⅡ, Determinations of Vaginal Flora, Plasma Female Sex Hormones and Vaginal pH Value / 第三军医大学学报

ABSTRACT

Vaginal flora, plasma estradiol and progesterone levels and vaginal pH value were determined in senile vaginitis patients.In 36 senile vaginitis patients, mean number of species per culutre for aerobic organisms was 1.47, that for anaerobes was 1.22 and that for all organism (including both aerobic and anaerobic)was 2.69.14 species of aerobic organisms were isolated from the vaginal discharge of the patients. They were staphylococcus aureus (27-8), staphylococcus albus(19.4%), Klebsiella sp(l6.7%), E- cloacae (13.9%), beta-streptococcus ( 11.1% ), diphtheroids(11.1%), alpha-streptococcus(8.3%), B- Coli(8.3%), E. hafnia (8.3%), E. agglomerans(8.3%), streptococcus faecalls(5.6%), gamma-streptoco-ccus(2.8%), Gaffkya tetragena(2.8%) and Hemophilus(2.8% ). 9 species of anaerobic organisms were detected:peptococcus(36.1%), Bacterodies(including B-fragilis, B. melangenicus and other Bacteroides 27.8%), Veillonella(22.2%), peptostreptococcus(16.7%), Lactobacillus(13.9), pusobacterium(2.8%) and C. pergrigens(2.8%). Both aerobic and anaerobic organisms were common indigenous vaginal flora.The mean concentration of plasma estradiol in 34 patients was 42.44?28.40 pg/ml, Concentration of plasma progestrone was determined in 9 out of the 34 patients. The mean value was 0.87?0.63 ng/ml. The levels of these female sex hormones were lower than those found in postmenopausal women reported from Shanghai.The mean pH value was 7.18?0.89. Deviation of vaginal pH to alkalinity may be either the precipitating factor or the result of senile vaginitis.Factors concerned with the pathogenesis of senile vaginitis were discussed.