METHOD FOR MEASURING IL-1 AND EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ( TGP ) ON IL-1 PRODUCTION / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1986.
Article
Dans Chinois
| WPRIM
| ID: wpr-550120
ABSTRACT
Method for measuring interleukin 1 ( IL -1 ) and effects of total glucosides of paeony(TGP) on IL -1 production were studied. The results showed that the best concentration for LPS -induced IL-1 production of M s in rats was 8mg/L, the best dilution for IL-1 of LPS-induced M s production was 1 90. TGP ( 0 .5 - 12 .5mg/L ) enhanced LPS-induced IL -1 production in a concentration dependent manner, but diminished in the higher concentration of TGP ( 62 .5~l25mg/L ) , the concentration-effect curve seems to be bell-shaped. The data suggested that TGP had two-sided regulatory effects on LPS -induced IL production of M s in rats.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Pharmacological Bulletin
Année:
1986
Type:
Article
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