Effects of Soman on Lymphocyte Proliferation in Mice / 第三军医大学学报
Journal of Third Military Medical University
; (24)1988.
Article
Dans Zh
| WPRIM
| ID: wpr-550122
Responsable en Bibliothèque :
WPRO
ABSTRACT
Effects of soman on lymphocyte proliferation are investigated in mice. 1 d after soman(154 ?g/kg,sc) poisoning B-lymphocyte reaction to lipopolysaccharide(LPS) is inhibited significantly and is persistent.T-cell proliferation response stimulated by concanavalin(Con A)has a 2-phase changeson the 1st day an increase followed by a dramatical reduction. Both the decreases of T-and B-lymphocyte mitogenic response and the primary increase of T-cell response show a close correlation with the doses of soman in this experiment. It has no relation to the change of the whole blood cholinesterase activity.
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Third Military Medical University
Année:
1988
Type:
Article