Histopathological and Ultrastructural Studies of Renal Tissues in Dogs with Severe Steam Respiratory Burns / 第三军医大学学报

ABSTRACT

This paper is to report the pathological changes in canine renal tissues after severe steam inhalation injuries. The specimens from 84 male mongrel dogs are studied with a light microscope, and 30 tissue samples of the 84 with an electron microscope. The morphological changes of glomeruli are characterized by, hypertrophy and/or hyperplasia of the glomerular cells, the former manifested as cell enlargement, increased amount of cytoplasm and rich in organelles; retrogressive changes of the glomerular cells in varying degrees as evidenced by intra-cellular edema. The renal tubules show varying degrees of degeneration, necrosis, and casts formation. Tubular necrosis affects more frequently the proximal convoluted tubules. The etiological factors of it are briefly discussed.