INVESTIGATION OF THE MECHANISMS OF INCREASE INSERUM HIGH DENSITY LIPOPROTEIN CHOLESTEROLBY CONCENTRATED FISH OIL IN RATS / 营养学报

ABSTRACT

In this experiment, we investigated with enzymological methods the mechanisms of increase in serum high density lipoprotein cholesterol (HDL-C) in rats fed with concentrated fish oil. The rats were fed with high fat diet (Group 1), high fat plus olive oil (Group 2) and high fat plus concentrated fish oil (Group 3) for 6 weeks respectively. The concentrated fish oil contained about 26% methyl-eicosapentaenoate (EPA-M) and 52% me-thyl-docosahexaenoate (DHA-M), and was given in 0.5ml/day for each animalThe results showed that HDL-C levels in the serum of rats fed with fish oil were markedly higher than Group 1 and 2 (p