Protective effects of ginseng root saponins on immunity in heat-stressed mice / 中国药理学通报

ABSTRACT

, 15min),the clearance of reticuloendothelial system (RES) of mice on iv charcoal particles were decreased apparently; serum hemolysin concentration were diminished notably; delayed type hypersensitivity (DTH) reaction induced by sheep red blood cell (SRBC) were inhibited obviously. Ginseng root saponins (GRS) 50, 100 mg ??? kg-1ip at 15min before the heat-stressprotected the immunity of mice from inhibitory effects induced by the heat-stressor. The suppression of the clearance of RES on charcoal particles,serum hemolysin concentration as well as DTH reaction induced by SRBC were all abolished by GRS.