THE ACUTE LUNG INJURY INDUCED BY E.COLI ENDOTOXIN AND THERAPEUTIC EFFECT OF PROSTAGLANDIN E_1 IN RABBITS / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)1981.
Article
Dans Chinois
| WPRIM
| ID: wpr-551201
ABSTRACT
A model of acute lung injury was reproduced by intravenous injection of endotoxin (700?g / kg) to rabbits. It had been found that the rabbits were in the state of shock, with leukopenia and thrombocytopenia, increased 6 -keto-PGF1? and TXB2, decreased serum ACE and increased permeability of the pulmonary capillaries. Granulocyte sequestration and disturbance in pulmonary microcirculation were found in lungs. A series of changes in epithelial and endothelial cells were also found in both lungs. It was obviously proved that PGE1 had some therapeutic effects in acute lung injury induced by E. coli endotoxin.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Medical Journal of Chinese People's Liberation Army
Année:
1981
Type:
Article
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