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Experimental research of anti-inflammatory action and immunoregulation on rabbit's brain phospholipids / 中国药理学通报
Article de Zh | WPRIM | ID: wpr-551490
Bibliothèque responsable: WPRO
ABSTRACT
Rabbit's brain phospholipids (RBP) 100~200 mg ?kg-1 ip or sc showed anti-inflammatory action on four kind of acute inflammatory animal models. Cephalin and Lecithin were the effective component of antiin-flammatory action on the acute inflammatory animal model. But RBP did not show antiinflam-matory action on the chronic proliferative inflammatory model. RBP increased blood carbon particle clearance, perfaneal macrophage phagocytosis and enhanced lymphocyte proliferation,hemolysin antibody in normal and immunode-pression animal. RBP increased the cGMP content in the liver tissue of immunodepression animal, 0. 1~1 mg ?L-1 RBP promoted proliferation but 100 mg ?L-1 RBP inhibited proliferation induced by PHA in vitro on human lymphocyte.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Pharmacological Bulletin Année: 1987 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Pharmacological Bulletin Année: 1987 Type: Article