THE THERAPEUTIC EFFECTS OF RECOMBINANT HUMANIZED ANTI-HER2 ANTIBODY (HERCEPTIN) ON HER-2/ NEU-OVEREXPRESSING METASTATIC IRJMAN BREAST CANCER / 解放军医学杂志

ABSTRACT

To investigate the therapeutic effects of recombinant humanized anti-HER2 antibody (Herceptin) on Her-2/neu-overexpressing metastatic human breast cancer, 7 patients with Her-2/neu-overexpressing metastatic human breast cancer were involved in this study. The results indicated that the therapeutic effective rate was 71. 4%. CR. PR, SD. PI) were seen in 2. 3, 1, 1 cases, respectively. No side reactions were observed. The results revealed that the therapeutic effect of Herceptin is intimately linked to Her-2/neu expression of breast cancer.