Effect of simulated altitude acute hypoxia on appetite and orexin mRNA expression in rats / 肠外与肠内营养
Parenteral & Enteral Nutrition
; (6)2004.
Article
de Zh
| WPRIM
| ID: wpr-555570
Bibliothèque responsable:
WPRO
ABSTRACT
Objective: To investigate the effects of simulated altitude acute hypoxia on appetite and orexin mRNA expression in rats. Methods: Rats were exposed to hypobaric chambersimulating different high altitude (3000m,4000m,5000m,6000m) for different times (8h/d;1d,3d and 7d respectively), and the changes of appetite, weight gain, and the orexin mRNA expression in hypothalamus of rats were examined. Results: With the increasement of hypoxia time and simulated altitude, the total food intake of rats and the orexin A and B mRNA expression in hypothalamus decreased gradually as compared with control. After 7 days of hypoxia, the weight gain of rats was significantly different(P
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Parenteral & Enteral Nutrition
Année:
2004
Type:
Article