Changes in nuclear factor ?B activity in peripheral blood mononuclear cell in newly diagnosed type 2 diabetes / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-558893
ABSTRACT
Objective To investigate the changes of nuclear factor?B activity in peripheral blood mononuclear cell(PMNC)in newly diagnosed type 2 diabetic patients.Methods Thirty normal individuals and 30 newly diagnosed type 2 diabetics were selected.Phosphorylation status of NF-?B P65 of PMNC was determined by immunoblotting with phosphor-specific antibodies to NF-?B P65(Ser 536 ).Serum hs-CRP was assayed by enzyme linked immunosorbent assay(ELISA).Results The level of NF-?B P65 phosphorylation was increased in newly diagnosed type 2 diabetic patients compared with control subjects[0.85(0.49,1.02)vs 0.47(0.26,0.67),P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude diagnostique
langue:
Chinois
Texte intégral:
Chinese Journal of Practical Internal Medicine
Année:
2001
Type:
Article
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