Curative Effect Observation of two Antibiotics for Neonatal Infection Pneumonia & the Research of their Affects on Intestinal Microflora / 医学研究杂志

ABSTRACT

Objective To explore the effect of antibiotics to neonatal intestinal microflora.Methods the neonatus who had infectious pneumonia were selected as case-groups,and divided into three sub-groups according to the antibiotics the patient used randomly.Tak- ing the period when all indexes were normal as pneumonia being cured,and curing rate and time-effect were compared among groups.To explore the effect of antibiotics to neonatal,the main microflora which can reflect the all intestinal microflora were quantitatively analysed when antibiotics had been used three and seven days respectively.Results The results showed that:①there is no significant difference on curing rate and time-effect among the three groups;②antibiotics showed effect to neonatal intestinal microflora,and the longer the antibi- otics was used,the more significant the effect was;③the group with penicillin and cynnematin simultaneously showed the most effect to in- testinal microflora,and the group with cynnematin only showed moderate effects on intestinal microflora,and the group with penicillin showed little effect to intestinal microflora.