Effect of maternal ethanol consumption during gestation on insulin sensitivity and adipokines in the rat offspring / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
Dans Zh
| WPRIM
| ID: wpr-561342
Responsable en Bibliothèque :
WPRO
ABSTRACT
Aim To investigate the effect of prenatal alcohol on insulin sensitivity of rat offspring and its underlying mechanism. Methods Female Sprague Dawley rats were given ethanol 4 g?kg-1?d-1 by gavage throughout pregnancy. At 16 wk of age, the rat offsrping underwent intravenous glucose tolerance test. The mRNA level of adipose leptin, resistin and adiponectin were determined by RT-PCR. Serum leptin, resistin and adiponectin were measured with RIA kits. Results Newborn ethanol rats had lower birth weight than control [(5.7?0.1) g vs (6.9?0.1) g,P
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Diagnostic_studies
langue:
Zh
Texte intégral:
Chinese Pharmacological Bulletin
Année:
1986
Type:
Article