Efficacy of adefovir dipivoxil in treating patients with hepatitis B resistant to lamivudine / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12)2004.
Article
Dans Chinois
| WPRIM
| ID: wpr-561890
ABSTRACT
AIM:
To evaluate the efficacy and safety of adefovir dipivoxil in treating patients with hepatitis B resistant to lamivudine.METHODS:
68 patients with hepatitis B resistant to lamivudine were administered 10 mg adefovir dipivoxil orally daily for over 1 years.The serum HBV-DNA levels were measured by quantitative PCR and liver function test,HBeAg/anti-HBe and safety assessments were also performed at 0,12,24,52 weeks after treatment.RESULTS:
After 12,24,52 weeks of treatment, the mean HBV-DNA levels were reduced by 1.6 lg copies/mL (t=10.10,P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Clinical Pharmacology and Therapeutics
Année:
2004
Type:
Article
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