THE METABONOMIC STUDY ON PORTAL BLOOD PLASMA OF RATS AFTER ORAL ADMINISTRATION OF QUERCETIN / 营养学报
Acta Nutrimenta Sinica
;
(6)2004.
Article
Dans Chinois
| WPRIM
| ID: wpr-562634
ABSTRACT
Objective:
To investigate the effects of quercetin on metabolic profiles of portal blood plasma in rats.Method:
Twenty five male Wistar rats were administered orally with 40 mg/kg bw quercetin. Portal blood was collected at 0,0.5h,1 h,2 h and 4 h after dosing respectively and analyzed by 1H NMR. The acquired data were subjected to partial least-squares discriminant analysis.Results:
The identified biochemical effects associated with quercetin dosing included increased plasma concentrations of dimethyl sulfoxide,lactate,glucose,alanine,glutamate,succinate,?-hydroxybutyrate,acetone and decreased plasma concentrations of citrate and tyrosine.Conclusion:
Quercetin may change the intestinal endogenous metabolism significantly in rats.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Acta Nutrimenta Sinica
Année:
2004
Type:
Article
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