Expression of neuroglobin after focal cerebral ischemia and its neuroprotective effect / 第二军医大学学报
Article
de Zh
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| ID: wpr-564376
Bibliothèque responsable:
WPRO
ABSTRACT
Objective:To study the expression of neuroglobin (Ngb) in rat cerebral ischemia model and the neuroprotective effect of Ngb after ischemia and hypoxia. Methods: Totally 113 Sprague-Dawley rats were randomly divided into sham-operated group, middle cerebral artery occlusion (MCAO) group, hemorrhagic infarction (HI) group and hemin treatment group. The brain water content, infarcted tissue volume, neuropathologic changes (H-E staining) and expression of Ngb (immunocytochemical staining) were examined 3, 6, 12, and 24 h after model establishment. Results: The brain water contents and the infarcted tissue volumes in the hemin treatment group were significantly different from those of the MCAO group and HI group (P
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Academic Journal of Second Military Medical University
Année:
2000
Type:
Article