Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs
Journal of Veterinary Science
;
: 123-126, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-56502
ABSTRACT
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tissu adipeux
/
Maladie aigüe
/
Résultat thérapeutique
/
Décompression chirurgicale
/
Transplantation de cellules souches mésenchymateuses
/
Maladies des chiens
/
Dégénérescence de disque intervertébral
/
Perception de la douleur
/
Déplacement de disque intervertébral
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Journal of Veterinary Science
Année:
2016
Type:
Article
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