Silent Colonic Malakoplakia in a Living-Donor Kidney Transplant Recipient Diagnosed during Annual Medical Examination
Korean Journal of Pathology
;
: 163-166, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-56546
ABSTRACT
Malakoplakia is a characteristic inflammatory condition, which is usually seen in the urogenital tract, and less frequently in the gastrointestinal tract. We present a case of colonic malakoplakia in an immunocompromised patient. A 55-year-old female visited the outpatient clinic for routine cancer surveillance. Her past medical history was significant for kidney transplantation 11 years ago, and she had been taking immunosuppressants. A colonoscopy revealed several depressed flat lesions and elevated polyps, which were 0.3 to 0.4 cm in size and accompanied by whitish exudates. A biopsy revealed an infiltration of histiocytes with ample granular eosinophilic cytoplasm, with some lymphocytes and plasma cells. Many histiocytes had the characteristic morphology, described as Michaelis-Gutmann bodies one or several round basophilic structures of approximately 1 to 10 microm in size with some being laminated, some appearing homogeneous, and others having a dense central core with a targetoid appearance. These Michaelis-Gutmann bodies were positively stained on von Kossa stain, and were diagnostic for malakoplakia.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plasmocytes
/
Polypes
/
Granulocytes basophiles
/
Biopsie
/
Lymphocytes
/
Coloscopie
/
Transplantation rénale
/
Sujet immunodéprimé
/
Côlon
/
Transplants
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Korean Journal of Pathology
Année:
2013
Type:
Article
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