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Inhibitive effect of Eqi-anticarcinogen Prescription on associated gene protein in process of rat hepatocarcinoma induced by diethylnitrosamine / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy ; (12)2005.
Article Dans Chinois | WPRIM | ID: wpr-567325
ABSTRACT

Objective:

To study the influence of the Ewi-anticarcinogen Prescription on associated gene protein in process of rat hepatocarcinoma induced by diethylnitrosamine (DEN).

Methods:

Rats hepatocarcinoma model was induced by DEN, while the Eqi-anticarcinogen Prescription was used during the stage. At the end of 12th week and 16th week, the influence of the Eqi-anticarcinogen Prescription on positive expression of PCNA and p53 protein were examined by immuneohistochemical method.

Results:

The positive expression of p53 protein was occurred in precancerous hyperp lastic nodules; The Eqi-anticarcinogen Prescription can significantly inhibit the overexpression of p53 (P

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: China Journal of Traditional Chinese Medicine and Pharmacy Année: 2005 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: China Journal of Traditional Chinese Medicine and Pharmacy Année: 2005 Type: Article