A PRELIMINARY STUDY ON RELATIONSHIP BETWEEN TOXOPLASMA INFECTION AND INTELLIGENCE DEFICIENCY IN CHILDEN / 重庆医科大学学报

ABSTRACT

This paper reports the results of latex agglutination (LA) and enzyme-linked immunoso-rbent assay (ELISA) for detecting the specifie anti-Toxoplasma antibody positive rates among 79 cases of intelligence deficiency children and their mothers, and 107 cases of intelligence-normal children and their mothers. The results indicated that between the results of LA and ELISA a good coincidence was presented.The anti-Toxoplasma antibody both positive rates of LA and ELISA wen 6.38, 8.36, O and 0.93% respectively. The both positive raves of intelligence deficiency children and mothers group were signifiantly higher than that of intelligence-normal children and mothers group. In 19 intelligence deficiency children with congenital malformation, the both positive rate was 15.79%, and was significantly higher than that of 107 intelligence-normal children (0%), and 60 intelligence deficiency without congenital malformation children (3.33%) respectively. Therefore,Toxoplasma infection may be one of the potential pathogenic causes of intelligence deficiency and congenital malformation in children. We suggest that routine examinations for anti-Toxoplasma antibody in pregnant women be carried out