Effects of Clausenamide on hippocampus COX-2 mRNA and protein expressions in diabetic rats / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1986.
Article
Dans Chinois
| WPRIM
| ID: wpr-567804
ABSTRACT
Aim To explore the effects of Clausena-mide(Clau) on hippocampus cyclooxygenase-2 (COX-2) mRNA and protein expressions in diabetic rats. Methods The diabetic rat model was produced by injecting streptozotocin (STZ,48 mg?kg-1). After 3 months,the COX-2 gene and protein expressions in hippocampus of diabetic rats were detected by RT-PCR and immunohistochemistry respectively. Results ① The results of RT-PCR showed that the expression of COX-2 mRNA in hippocampus of diabetic group rats increased significantly (P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Pharmacological Bulletin
Année:
1986
Type:
Article
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