SUBSTANCE P-IMMUNOREACTIVE NERVE FIBERS IN THE PARS DISTALIS OF THE ANTERIOR PITUITARY OF MACAQUES / 解剖学报

ABSTRACT

The anterior pituitary gland of Macaca mulatta and M. assamensis were stained with antiserum against substance P. A substantial amount of substance P-immunoreactive (SP-ir) nerve fibers with numerous varicosities were found in the pars distalis of the anterior pituitary. They were located in the median part of the gland and were distributed mainly in its dorso-posterior region. The great majority of the varicosities were found to be related to the glandular tissue, although some apparently were located along the wall of the blood sinuses. Also many SP immuno reactive cells, mostly large and oval, and were distributed at the periphers of the gland. In areas where both SP-ir nerve fibers and cells were present, many cells were found to be in close proximity to nerve fibers.