The role of CA_(125)in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract / 中华妇产科杂志

ABSTRACT

Objective To assess the role of CA 125 monoclonal antibody in the differential diagnosis of primary ovarian carcinoma and metastatic ovarian carcinoma originated from the gastrointestinal tract Methods Immunohistochemical study using CA 125 monoclonal antibody was performed on 33 primary ovarian cancer and 50 metastatic ovarian cancer of gastrointestinal origin Results The positivity of CA 125 was 84 5% in 33 cases of primary ovarian carcinoma, while in 50 metastatic ovarian carcinoma cases, only 4 0% was CA 125 positive The positivity of CA 125 was significantly higher in primary ovarian carcinoma than metastatic ovarian carcinoma ( P