Influence of the sperm DNA integrity on ART result / 中国基层医药

ABSTRACT

Objective To explore the relationship between the sperm DNA integrity and ART result.Methods Employ improved SCD test for sperm DNA integrity assay.Meanwhile,statistical methods was used for data analysis.Results After compaed the infertility rate( IVF77.4％ vs 84.8％,P =0.366;ICSI90.1％ vs 92.1％,P =0.899),cleavage rate ( IVF97.1％ vs 96.4％,P =0.958 ; ICSI96.0％ vs 99.0％,P =0.845 ),high-quality embryo rate ( IVF42.8％ vs 38.6％,P =0.485 ; ICSI25.8 ％ vs 46.2％,P =0.002 ) and pregnancy outcome ( IUI13.8％ vs 16.6％,P =1.000;IVF35.3％ vs 73,7,P =0.150;ICSI49.5％ vs 42.8,P =0.832) between the populations with normal and abnormal sperm DNA integrity during ART therapy,there is no statistical difference was found except high-quality embryo rate with ICSI therapy.Conclusion Sperm DNA integrity value can't be used to predict the ART outcomes independently.