The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis
Annals of Surgical Treatment and Research
;
: 17-22, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-57053
ABSTRACT
PURPOSE:
The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses.METHODS:
Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats and assigned to an oxygen/nitrous oxide mixture with a fraction of inspired oxygen of 30% in groups 1 and 3 and 80% in groups 2 and 4. The measurements of perianastomotic tissue oxygen pressure, bursting pressure, level of hydroxyproline were evaluated and compared in all groups.RESULTS:
The perianastomotic tissue oxygen pressures, bursting pressures and levels of hydroxyproline were identified as significantly high in groups 2 and 4, administered a fraction of inspired oxygen of 80%, compared to groups 1 and 3, administered a fraction of inspired oxygen of 30%.CONCLUSION:
Perioperative supplemental oxygen contributes positively to the anastomotic healing.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oxygène
/
Ventilation
/
Rat Wistar
/
Hydroxyproline
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Animaux
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Annals of Surgical Treatment and Research
Année:
2015
Type:
Article
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