Off-Pump coronary artery bypass grafting: clinical study on myocardial protection / 中华胸心血管外科杂志

ABSTRACT

Objective: To compare the myocardial protection effect between off-pump coronary artery bypass(OPCAB)and on-pump coronary artery bypass. Methods: 70 patients were divided into 2 groupsoff-pump coronary artery bypass(beating group,n=35), and cold blood cardioplegia solution group(cold group,n=35). There was no statistical difference in heart function, sex, age and weight before operation. Blood samples were taken for determine the serum concentration of creatine kinase MB isoenzyme (CK-MB) and troponin-T(cTnT) peri-operatively. Myocardial ultrastructure was also observed. Results: CK-MB, cTnT release in beating group during bypass and post-bypass was lower than that in cold group (P