Single lung transplantation in treatment of severe emphysema / 中华胸心血管外科杂志

ABSTRACT

Objective: To treat the senile severe emphysema by single lung transplantation. Methods: The candidate was a 63-year-old male patient who had suffered from severe dispnea for more than 23 years and experienced an advancing exacerbation during the last 3 years. He showed very poor lung function and other related clinical date the pre-operative clinical examination: FEV 1 was 0。64L (24%), PaO 2 was 45 mm?Hg, PaCO 2 was 36。3 mm?Hg, pulmonary artery pressure is 38 mm?Hg, 6MMT was 59 m and dispnea staging was 4. An allograft left lung transplantation was performed under general anesthesia in January 9th, 2003. Three immunosuppressors were given to the recipient orally after the operation. Results: 6 months after lung transplantation, the recipient showed a significant clinical relief and lung function improvement: FEV 1 is 1.20L (40%), PaO 2 is 92 mm?Hg and 6MMT is 227 m. Conclusion: The single lung transplantation is efficient in treating the end-staged emphysema.