Effects of diazoxide-cardioplegia on electrophysical properties of guinea pig myocardium / 中华胸心血管外科杂志
Chinese Journal of Thoracic and Cardiovascular Surgery
;
(12)2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-571825
ABSTRACT
Objective:
To observe the effect of on modified St.Thomas solution with mitochondrial ATP-sensitive potassium channel opener diazoxide on guinea pig papillary muscles protection after myocardial hypoxia.Methods:
Twenty-four guinea pigs were randomly divided into three groups. In control group, cardioplegia was routine St.Thomas solution. In treatment group, cardioplegia was used modified St.Thomas solution. In blocker group, the muscle was treated with the specific potassium channel blocker glibenchamide 15 minutes before arrest used diazoxide cardioplegia. Myocardial electrophysical before and after cardioplegic arrest in guinea pig papillary muscles were studied.Results:
1, Time of recovery was shortened significantly in treatment group (P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Thoracic and Cardiovascular Surgery
Année:
2003
Type:
Article
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