Effects of diltiazem on angiographic and clinical outcomes in patients with chest pain following coronary stenting / 介入放射学杂志

ABSTRACT

Objective To evaluate the effects of diltiazem on angiographic and clinical outcomes in patients with postprocedural chest pain after coronary stenting. Methods Two hundred and fifty-one patients with postprocedural chest pain were divided into two groups diltiazem group (n = 189) and control group (n = 62). The outcomes of the two groups were compared according to the following two points. The first point was the major adverse cardiac events, including mortality, nonfatal infarction and target lesion revascularization. The second point was restenosis during the follow-up period. Results By the median of 128 days, the severe composite clinical events reached 4.8% in the diltiazem group and at 12.9% in the control group (P = 0.039). Repeated angiography was performed in 42.6% of these patients within one-year showing 11.5% restenosis in the diltiazem group and 29.2% in the control group (P = 0.05). Conclusions In patients with postprocedural chest pain after coronary stenting, oral diltiazem contributes a favorable outcome. (J Intervent Radiol, 2006, 15 261-263)