Determining metabolite diosgenin of Ophiopogon japonicus saponin in vivo by HPLC-MS / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Article
Dans Chinois
| WPRIM
| ID: wpr-575656
ABSTRACT
AIM:
To determine the low content of Ophiopogon japonicus saponin metabolite in vivo.METHODS:
HPLC-MS method of determining rat's metabolite diosgenin in vivo was established after single-dose oral Ophiopogon japonicus saponin enteric microsphere.RESULTS:
The detection limit was about 50 ng/mL,Linearity,precision of intra and inter-day and reproducibility of the method were good.CONCLUSION:
This method accords with the analysis requirement.It can give an effective measure and foundation for studying TCM saponin bioavailability.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Traditional Patent Medicine
Année:
1992
Type:
Article
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