Chemical constituents of antirheumatism fraction from Urtica fissa / 中草药

ABSTRACT

Objective To study the chemical constituents of the EtOAC soluble fraction from Urtica fissa with obviously anti-inflammatory and analygestic effect. Methods The compounds were isolated by polyamide and silical gel colum chromatography and identified by UV, IR, NMR, and MS. Results Twelve compounds were isolated from U. fissa and identined as quercetin (Ⅰ), kaempferol (Ⅱ), kaempferol-3-O-?-D-glucopyranoside (Ⅲ), quercetin-3-O-?-D-glucopyranoside (Ⅳ), caffeic acid (Ⅴ), chlorogenic acid (Ⅵ), scopolin (Ⅶ), scopoletin (Ⅷ), kaempferol-3-O-rutinoside (Ⅸ), quercetin-7-O-?-D-glucopyranoside (Ⅹ), isorhamnetin-3-O-?-D-rutinoside (Ⅺ), ?-sitosterol ( ⅩⅡ ). Conclusion Compounds Ⅰ-Ⅺ are all isolated from U. fissa for the first time and compounds Ⅶ, Ⅹ, and Ⅺ are found in plants of Urtica L. for the first time also.