The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation / 重庆医科大学学报

ABSTRACT

Objective:The aim of this study is to explore pretransplantation MELD score in predicting shortterm survival of patients with endstage liver disease post liver transplantation.Methods:We studied 3 months and 6 months patient survival in 33adult patients who underwent liver transplantation between January 2000 and November 2005 in our hospital.The MELD score pretransplantation was recorded.We shared categories of their MELD score(≤20,21~30,≥30)and compared their survival.In our study,we also compared urine volume(ml/h)of the patients during operation.Results:The total survival rates in 3 month and 6 months after transplantation were respectively 90.1%(30/33)、81.8%(27/33),there were respec-tively100.0%、92.3%(P =0.861)in those patients with a MELD score of lower 20 and 21~30 in 3 monbhs swwival rate,they had no significance.We found only those patients with a MELD score of 30 or higher had a survival that was markedly lower than the rest(P =0.012 and 0.041)in 3 months survival rocte.The urine volume(ml/h)of survival patients whese survival time exceeded 3 months during operation(126.2?118.9m1/h)was obviously higher than the dead ones within 3 months(25.3?22.6ml/h),they were significant(P =0.0001).Conclusions:1 The ability of the pretransplantation MELD score to predict short-term survival of patients with end-stage liver disease post liver transplantation is uncomplerely,because they do not have linear relation and there is a threshold in the MELD score beyond which survival decreases in such a fashion.2 The urine volume(ml/h)during operation can predict the lesion of Kidney from the factors before and during operation.It also correlates to the risk of patients post-transplantation.