Analysis of imaging presentation of solitary plasmacytoma in 17 cases / 重庆医科大学学报

ABSTRACT

Objective:To improve diagnostic ability by the evaluation of imaging appearances of solitary plasmacytoma.Meth-ods:Seventeen patients with solitary plasmacytoma confirmed by biopsy or operation were included in our study,whose clinical features and diagnostic imaging appearances were included.Results:Single lesion was found in all cases;Lesions of vertebra in 5 cases,flat bone in 5 cases,pipe bone in 2 cases and outside the bone in 5 cases.The Lesions in bone showed expansive osteolytic with clear border,soft tissue mass nearby,and thin and broken cortical.Vertebra lesions showed lytic destruction and compressed fracture.MRI showed slightly hypointense in T1WI and hyperintense in T2WI with markedly homogeneous enhancement.Lesions outside the bone appeared soft tissue mass with similar density to muscle in CT and X ray,and isointen-sity in T1WI and T2WI with markedly homogeneous enhancement.Lesions in ECT showed medium-to-high nuclide concentration,and in PET/CT showed the increase of glucose metabolize,with SUV 6.3～8.6.About one month after effective chemical therapy,soft tissue mass shrank obviously and new bone appeared,with the decrease of glucose metabolize,and SUV under 2.0.Conclusion:Solitary plasmacytoma often occurs in male,and in younger age and lacks symptoms in the whole body compared with multiple myeloma.Lesions in different regions show different manifestations,but all borders are well defined.CT and MRI can depict the extent of solitary plasmacytoma of bone clearly,but MRI was better in showing bone marrow infiltration range,and showing compression of spinal cord.PET/CT are more suitable in follow-up therapy.