The expressions of ICAM-1 and VCAM-1 in HIE neonatal rabbits / 重庆医科大学学报

ABSTRACT

Objective:Searching after the effects of the expressions the neonatal rabbits with chronic intrauterine anoxemia give to neutrophil and conglutinated molecule.Method:Choosing 15 Zelanian rabbits that have been in afternoon pregnancy,we divide them into three stochastic contratest groups by chancethe control group,the anoxic group and the group interfered with Chinese traditional medicine.Then,we contrast the expressions and changes of these groups with CD11b/CD18,ICAM-1 and VCAM-1.Results:Contrasting the CD11b/CD18,ICAM-1 and VCAM-1 of the anoxic group and the group interfered with Chinese traditional medicine with chinese traditional medicine with the control group,we have found their expressions all more remarkably strengthened;There is some difference in expression between the anoxic group and the group interfered with Chinese traditional medicine,but it has little statistical significance.Conclusion:In this article,there occurs the mentionthe chemotaxis of neutrophil has been strengthened and the endotheliocytosis of cerebrovascular has been conglutinated under anoxemia;as a result,the chemotaxis and endotheliocytosis have marred the brain cell tissue and participated in whole pathological and physiological process.