EFEECT OF AQUROUS BXTRAOCI FROM MYTRUS EDULIS ON ISOLATED UTERUS SMOOTH MUSCLE OF RAT / 中国海洋药物

ABSTRACT

The article first reported the effect of aqueous extract of mytilus edulis (AEME) on isolated uterus of rat and mechanism of action. The result showed that AEME had a contraction effect on rat uterus,both amplitude quantity and frequency were increased. Also AEME potentiated contractions to field stimulation of rat vas deferent. These actions were blocked by alpha - receptor blocking agent phentolaming. However,it were relaxation on ileum and stomach strip of rat. These relaxations were blocked by phentolamine too. The volume of flow were decreased,it was from 47+11 dr/min to 24 + 7 dr/min,( P