Detection and Drug-resistance Analysis of ESBLs-producing Bacteria / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To comprehend antimicrobial susceptibility distribution of the ?-lactamases products from Feb 2002 to Feb 2003 in our hospital.METHODS The Microscan-USA was used to identify pathogens and drug sensitivity tests,the results of examination were judged according to NCCLS 1999 standard.(RESULTS) Among the isolated 67 strains of ESBLs-producing bacteria(35.64%),31 strains of(Klebsiella) pneumoniae(36.05%),29 strains of Escherichia coli(43.28%), 6 strains of Enterobacter cloacae((22.22)%)and 1 of K.oxytoca(12.5%) were detected.The multi-resistance of ESBLs~+ bacteria was very usual,besides to the ?-lactam antibiotics.The pattern of being resistant to both of tobramycin and ciprofloxacin was relatively common,and amikacin was relatively less,even the complex antibiotics containing ?-lactamases inhibitor would lose their effect.(CONCLUSIONS)The ESBLs bacteria exist in our area at a high level and also be the main antimicrobial-resistant ones and have got the resistance to many kinds of antibiotics.To control the(ESBLs)~+(bacteria) infection,expanding and supervision management of antibiotics is a urged task and important for us.