Clinical significance of granuloma in Crohn's disease / 基础医学与临床

ABSTRACT

Objective To explore the clinical significance of granuloma in Crohn's disease through the comparison of the clinical features between the groups with and without granuloma.Methods Seventy-five patients,hospitalized in Peking Union Medical College Hospital from 1995 to 2005,were retrospectively analysed.Results Compared with the nongranuloma group,the granuloma group shows increased disease activity,more frequent usage of immunosuppressant,higher operation rate and more postoperation complications.Conclusions Granuloma may be an index of the severity of disease activity in Crohn's disease.