Prospective Comparison of Dual Wavelength Long-Pulsed 755-nm Alexandrite/1,064-nm Neodymium:Yttrium-Aluminum-Garnet Laser versus 585-nm Pulsed Dye Laser Treatment for Rosacea
Annals of Dermatology
;
: 607-614, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-59027
ABSTRACT
BACKGROUND:
Rosacea treatments including oral/topical medications and laser therapy are numerous but unsatisfactory.OBJECTIVE:
To compare the effectiveness of the dual wavelength long-pulsed 755-nm alexandrite/1,064-nm neodymium yttrium-aluminum-garnet laser (LPAN) with that of 585-nm pulsed dye laser (PDL) for rosacea.METHODS:
This was a randomized, single-blinded, comparative study. Full face received four consecutive monthly treatments with LPAN or PDL, followed-up for 6 months after the last treatment. Erythema index was measured by spectrophotometer, and digital photographs were evaluated by consultant dermatologists for physician's global assessment. Subjective satisfaction surveys and adverse effects were recorded.RESULTS:
Forty-nine subjects with rosacea enrolled and 12 dropped out. There were no significant differences between LPAN and PDL in the mean reduction of the erythema index (p=0.812; 3.6% vs. 2.8%), improvement of physician's global assessment (p=1.000; 88.9% vs. 89.5%), and subject-rated treatment satisfaction (p=0.842; 77.8% vs. 84.2%). PDL showed more adverse effects including vesicles than LPAN (p=0.046; 26.3% vs. 0.0%). No other serious or permanent adverse events were observed in both treatments.CONCLUSION:
Both LPAN and PDL may be effective and safe treatments for rosacea.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Études prospectives
/
Rosacée
/
Consultants
/
Érythème
/
Thérapie laser
/
Lasers à colorant
/
Néodyme
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Annals of Dermatology
Année:
2016
Type:
Article
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