D-glucosamine hydrochloride(GAH) induce lymphocyte proliferation through Ca~(2+) signal pathway / 中国海洋药物
Chinese Journal of Marine Drugs
;
(6)2000.
Article
Dans Chinois
| WPRIM
| ID: wpr-590538
ABSTRACT
Objective To study the effect of GAH on lymphocytes proliferation and its mechanism. Methods MTT, fluorescence probe and immunofluorescent methods were used to investigate the effects of GAH on the lymphocytes proliferation, intracelluar Ca2+ concentration and expression of calcineurin(CaN). Results GHA induced lymphocyte proliferation, raised the intracelluar Ca2+ concentration and calcineurin expression. Conclusions GAH is a new kind of activator, which can induce lymphocyte proliferation through Ca2+ signal pathway.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Marine Drugs
Année:
2000
Type:
Article
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