Antibacterial Activity of Cefepime Combined with Sulbactam for Carbapenem-resistant Acinetobacter spp / 中华医院感染学杂志
Chinese Journal of Nosocomiology
; (24)2006.
Article
de Zh
| WPRIM
| ID: wpr-591149
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE To study the in vitro activity of cefepime combined with sulbactam against carbapenem-resistant strains of Acinetobacter spp clinically isolated. METHODS The activity of each drug alone was determined against 24 isolates. Chequerborad synergy testing was then performed against all the isolates. RESULTS The percentage of the FIC index showed 33.3% synergism, 62.5% additive, 4.2% (1/24) indifference, and no antagonism tively. CONCLUSIONS Testing of cefepime and sulbactam combinations revealed synergism and additivity activity against some carbapenem-resistant strains(23/24) of Acinetobacter spp which could be likely to prove beneficial effect for the treatment of infections due to multidrug-resistant strains of Acinetobacter spp.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Nosocomiology
Année:
2006
Type:
Article