Pathogens and Drug-resistant Pattern in General Hospital:2002-2005 / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To observe bacterial changing-pattern and drug-resistant pattern for reasonable application of antibiotics.METHODS We reviewed the data of 2002-2005 pathogens tests.RESULTS Of 6041 isolated pathogens,2765(45.8%) were Gram-negative bacilli,1350(22.3%) were Gram-positive cocci and 1926(31.9%) were fungi.Fungi increased almost twice,from 18.4% in 2002 to 36.4% in 2005.The most common Gram-negative bacilli were Escherichia coli,Klebsiella pneumoniae and Pseudomonas aeruginosa.While the most common Gram-positive cocci were Staphylococcus epidermidis,S.aureus and Enterococcus faecium.Compared with that in 2002,MRSA,MRSE,ESBLs-producing and AmpC-producing bacilli were significantly increased.Neither strains of S.epidermidis nor strains of S.aureus were found resistant to vancomycin.Carbapenems were the most active antibiotics tested against Gram-negative organisms.CONCLUSIONS We should recognize drug sensitive test as well as restrict the indication of antibiotics application,in order to reduce the occurrence of bacterial resistance.