Comparative analysis of lung puncture liquid-based cytology and histopathology / 医学研究生学报

ABSTRACT

Objective: The Thinprep liquid-based cytology test(TCT) is a new technique applied to cytopathologic diagnosis in recent years.The purpose of this study was to analyze the diagnostic coincidence between lung puncture liquid-based cytology and histopathology.Methods: A total of 408 tissue specimens obtained by CT-guided percutaneous translung biopsy were observed under the optical microscope after fixation,embedding,sectioning and staining,and the cells in the washing fluid for puncture needles were detected by TCT.Then the diagnostic coincidence was analyzed between cytological and pathological biopsies.Results: Of the 408 cases detected by liquid-based cytology,148(36.3%) were diagnosed as cancer,32(7.8%) as suspected cancer,38(9.3%) as heterocyst and 190(44.9%) were negative,as compared with 183(44.9%),21(5.1%),22(5.2%) and 182(44.6%) by histopathology.The results showed a correlation between the two methods(P