Drug Resistance of 449 Pathogenic Strains / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To find out the distribution and durg resistance of the pathogens in 2008 in the 8th People′s Hospital of Guangzhou.METHODS Disc diffusion test(KB methods) was employed to study the antimicrobial susceptibility.WHONET 5.3 was applied for date analysis.RESULTS 208 Gram positive coccus strains accounted for(46.3%),241 Gram negative bacillus strains(53.67%) in A total of 449 pathogenic strains.Meticillin resistant strains accounted for 41.7%and Staphylococcus aureus and CNS for 55%.All the Staphylococcus strains were not Vancomycin-resistance.Escherichia coli and Klebsiella pnenmoniae strains producing extended spectrum-beta-lactamas accounted for 41.4%and 44.2%,but were highly sensitive to Carbapenem.Acinetobacter baumannii and Pseudomonas aeruginosa were highly sensitive to Carbapenem.CONCLUSIONS The resistance of antibiotics should be continuously monitored to provide basis for reasonable use of drugs in clinical practice and take effective evidence for the control of the problem.