Toxic Effect of Organic Extracts From Chlorinated Drinking Water on Sertoli Cells of Testis in Rats / 环境与健康杂志

ABSTRACT

Objective　To explore the potential hazards of organic pollutants in chlorinated drinking water on human reproduction.Methods　The reproductive toxicity of the organic pollutants extracted by solid phase extraction technique from chlorinated drinking water in a city,was determined by the co-culture of sertoli cells and spermatogenic cells.Results　No significant variation of the rate of detached spermatogenic cells was noticed compared with the control rats.The organic extracts stimulated the secretion of lactate from sertoli cells of testis in rats.Conclusion　The organic extracts of chlorinated drinking water revealed potential reproductive toxicity.