The expression research of CD133 in mouse kidney / 重庆医学

ABSTRACT

Objective To observe the expression of CD133 in mouse kidney ,analysis the distribution pattern ,and provide basis for the kidney regeneration research .Methods The mice kidney was took by the heart perfusion fixation ,and then made into 5 μm thick slice .Immunohistochemistry test was used to detect the CD133 expression .Results CD133 was mostly expressed in renal pa-pallie zone ,and also could be seen at the distal tubule in outer zone of medulla external and the distal tubule in the superfacial neph-ron .Conclusion The renal papallie zone might have mass renal stem cells and regeneration capacity .