Causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test / 中国免疫学杂志
Chinese Journal of Immunology
; (12): 795-797,802, 2015.
Article
de Zh
| WPRIM
| ID: wpr-601507
Bibliothèque responsable:
WPRO
ABSTRACT
Objective:To investigate the causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test. Methods:We performed a hospital-based,case-control study of 4 050 patients with non-syndromic cleft lip and palate and 8 547 control patients without cleft lip and palate to evaluate associations between positive anti-HCV and non-syndromic cleft lip and palate. CLIA test were used for detect anti-HCV in control group. RIBA and FQ-PCR were used for confirming the result of the positive samples of CLIA test. CLIA test were used for detect anti-HCV in case group until CLIA test was negative. IgG,RF and ANA were used for case-control comparisons. Results:The detection rate of anti-HCV were higher in the case group than that of control group (P<0. 05). The false-positive rate was 1 percent based on testing of 4 050 patients. These samples were negative after opration 1-19 months. There were no change among IgG, RF and ANA in the false-positivepatients. Conclusion: False-positive anti-HCV in non-syndromic cleft lip was possible associated with abnormal plasma metabolic product. It can be excluded by track monitoring.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
langue:
Zh
Texte intégral:
Chinese Journal of Immunology
Année:
2015
Type:
Article