Effect of rosuvastatin combination probucol on patients with carotid atherosclerotic plaque / 中国医学装备
China Medical Equipment
;
(12): 92-94,95, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-602370
ABSTRACT
Objective:
To analyze the effect of rosuvastatin combination probucol on patients with carotid atherosclerotic plaque.Methods:
Chosen patients with carotid atherosclerotic plaque in our hospital as research subjects, randomly assigned to control group received probucol alone and observation group received rosuvastatin combined probucol, compared IMT and OX-LDL levels inflammatory factors levels, incidence of adverse.Results:
1)Observation group patients’ IMT and ox-LDL levels after treatment were significantly lower than control group patients(t=4.327,t=5.783;P<0.05); 2)Observation group patients’ hs-CRP, IL-6 and MMP-9 levels after treatment were significantly lower than control group patients (t=6.422,t=5.184,t=5.291;P<0.05); 3)Follow-up of 5 years, observation group patients vascular occlusion, plaque off , brain stem rate were significantly lower than control group patients (x2=4.827, x2=5.894,x2=5.937;P<0.05).Conclusion:
Rosuvastatin can effectively reduce joint Probucol carotid atherosclerosis intima-media thickness sclerosis patients and reduce the level of oxidized LDL, inflammatory cytokines optimization, and ultimately reduce the incidence of adverse events, with positive clinical significance.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
China Medical Equipment
Année:
2015
Type:
Article
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