The relationship between allergic, non-allergic rhinitis and obstructive sleep apnea-hypopnea syndrome / 天津医药

ABSTRACT

Objective To investigate the relationship between allergic rhinitis (AR), non-allergic rhinitis (NAR) and obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods Forty-eight patients with AR symptoms and snoring symptoms for at least 2 years, who received treatment in our outpatient, were included in this study. Skin prick test, serum specific IgE, polysomnography (PSG), acoustic rhinometry, nasal resistance (RM), Müller's test (FPMM) and Epworth sleepi?ness scale (ESS) were performed in patients. Results There were 25 AR patients (AR group) and 23 NAR cases (NAR group). ESS>9 scores were found in 19 patients, including 15 NAR cases and 4 AR cases. There was higher incidence of drowsiness in NAR group than that of AR group (P<0.05). Results of PSG showed that there were significantly higher proportions of apnea, poor sleep quality, AHI index, and lower values of the lowest oxygen saturation (LSpO2) and mean oxygen saturation (ASpO2) in NAR group than those of AR group (P<0.05). The incidence of OSAHS was significantly higher in NAR group than that of AR group (82.6%vs 36.0%, P<0.05). Conclusion Both AR and NAR were risk factors for OSAHS, and both can induce sleep disorders. NAR patients were more likely to result in OSAHS, and showing higher disease severity. NAR may have an important role in the initiation of OSAHS.