Literature Analysis of 56 Cases of Adverse Drug Reactions Induced by Monosialotetrahexosylganglioside Sodium Injection / 中国药房
China Pharmacy
; (12): 1067-1069,1070, 2016.
Article
Dans Zh
| WPRIM
| ID: wpr-605260
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE:
To study the general pattern,characteristics and related risk of adverse drug reaction(ADR)induced by Monosialotetrahexosylganglioside sodium injection,and to provide reference for safe use of drugs in the clinic.METHODS:
Us-ing“monosialotetrahexosylganglioside”and“ADR”as keywords,literautres were retrieved from CJFD,Wanfang and VIP database according to inclusion and exclusion criteria in Oct. 2014,and cases reports were extracted and analyzed statistically.RESULTS:
A total of 19 literatures were included,involving 56 patients,with the ratio of male to female was 6.17∶1,and the most of patients aged 0-9 years,≥60 years,accounting for 44.64%(25 cases),30.36%(17 cases). Multiple organs or systems were involved in ADR;the most common reactions are fever (29 cases) and shiver (28 cases),etc.,and severe ADR can cause green-barry syn-drome,anaphylactic shock,etc.CONCLUSIONS:
Thus,it is important to pay attention to ADR caused by Monosialotetrahexosyl-ganglioside sodium injection,to prevent the occurrence of serious ADR,to perfect drug instructions,and to ensure clinical safe ad-ministration.
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WPRIM
langue:
Zh
Texte intégral:
China Pharmacy
Année:
2016
Type:
Article