Retrospective Analysis of Two Low-flow Anesthesia Drugs for Pediatric Laparoscopic Operation / 中国药房

ABSTRACT

OBJECTIVE:To evaluate therapeutic efficacy and safety of two low-flow anesthesia drugs for pediatric laparoscop-ic surgery. METHODS:72 children underwent laparoscopic surgery in our hospital during Jan. 2012 to Dec. 2014 were collected retrospectively,and divided into trial group and control group,with 36 cases in each group. According to body weight,trial group was given sevoflurane 0.1 mg/kg and oxygen flow rate 0.6 L/min for anesthesia before surgery. The anesthesia induction time,AP, HR,SpO2 and pEtCO2 before surgery,during anesthesia induction and maintenance of anesthesia and at the end of surgery,recov-ery time,extubation time,dysphoria,nausea and vomiting after awake up were compared in 2 groups. RESULTS:Compared with before anesthesia,AP,HR and pEtCO2 of 2 groups were increased significantly,with statistical significance(P0.05). HR,AP and pEtCO2 of trial group were lower than those of control group after pneumoperitoneum,with statistical significance(P<0.05). After operation,recovery time,extubation time and the proportion of dysphoria in trial group were shorter or lower than control group, with statistical significance (P<0.05). CONCLUSIONS:The sevoflurane anesthesia has little effect on blood pressure and HR of patients,has short recovery time and extubation time,little side effects and good clinical efficacy.